Presumptive Y-15 and Y-22 translocation in two families
نویسندگان
چکیده
منابع مشابه
Presumptive C-15 translocation and familial large Y identified by autoradiography.
Translocations between Cand D-group chromosomes are relatively uncommon. Only 4 cases of such a translocation have been reported up to now. In 2 of these, autoradiographic studies (Pitt et al., 1967; Bloom and Gerald, 1967) identified the missing D-group chromosome as a No. 14 and a No. 13, respectively. The present paper presents a case of C/15 translocation in a child with psychomotor retarda...
متن کاملPresumptive Y/D translocation in mixed gonadal dysgenesis.
One of the important findings of human cytogenetics has been the role of the Y chromosome in testicular differentiation of the bipotential embryonic gonad, but a puzzle has been posed by reports of individuals with a testis but with no apparent Y chromosome. This paper describes a patient with mixed gonadal dysgenesis (testis and streak), interpreted as having a Y/D translocation in some cells,...
متن کاملSeminoma in a postmenopausal woman with a Y;15 translocation in peripheral blood lymphocytes and a t(Y;15)/45,X Turner mosaic pattern in skin fibroblasts.
We report an unusual case of a 55 year old Japanese woman with a seminoma but relatively normal menses. The patient was a phenotypic female with late onset menarche (18 years of age), who was amenorrhoeic for the first year, followed by menses of one to three days' slight flow with dysmenorrhoea, but an otherwise normal menstrual history. A typical seminoma was removed from the left adnexal reg...
متن کاملCytogenetic, molecular and testicular tissue studies in an infertile 45,X male carrying an unbalanced (Y;22) translocation: case report.
(Y;autosome) translocations have been reported in association with male infertility. Different mechanisms have been suggested to explain the male infertility, such as deletion of the azoospermic factor (AZF) on the long arm of the Y chromosome, or meiosis impairment. We describe a new case with a de novo unbalanced translocation t(Y;22) and discuss the genotype-phenotype correlation. A 36 year ...
متن کامل-Y, Y loss in leukemia
Note Loss of the Y chromosome from individual metaphases is common in metaphase cells from both PHAstimulated lymphocytes and spontaneously dividing bone marrow cells. The frequency of Y loss is greater in older men, and the size of the 45,X,-Y cell population probably increases gradually with advancing age. (In females, a corollary loss of one X chromosome also occurs with advancing age.) This...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hereditas
سال: 2009
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1972.tb01031.x